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PPI network of S-plot proteins (p(corr) ± 0.80) manifesting in the stage I–II OPSCC. The five serum proteins discussed in the article as possible biomarkers for early-stage OPSCC and suggested for further screening are circled: CFHR2 and MYL12A, upregulated in the tumour patients’ serum are circled with red, and the downregulated C9, FCN3 and C4BPA are circled with green
