Table 2.
Relationship between fusion genes revealed by RNA-seq and clinicopathological characteristics in 147 patients with colorectal cancer
| (No.) | Fusion genes | P value | ||
|---|---|---|---|---|
| Absent | Present | |||
| Age (years) | 147 | 60.1 ± 1.00 | 60.7 ± 2.73 | 0.852 |
| Size (cm) | 147 | 5.81 ± 0.19 | 4.76 ± 0.33 | 0.050 |
| Sex | 0.819 | |||
| Male | 77 | 68 (88.3) | 9 (11.7) | |
| Female | 70 | 60 (85.7) | 10 (14.3) | |
| Location | 0.162 | |||
| Right colon | 56 | 46 (82.1) | 10 (17.9) | |
| Left colon | 91 | 82 (90.1) | 9 (9.9) | |
| Histological typea | 0.093 | |||
| Well | 27 | 23 (85.2) | 4 (14.8) | |
| Moderately | 111 | 99 (89.2) | 12 (10.8) | |
| Poorly + Mucinous | 9 | 6 (66.7) | 3 (33.3) | |
| Invasion depthb | 0.463 | |||
| T1 | 1 | 1 (100.0) | 0 (0.0) | |
| T2 | 16 | 13 (81.3) | 3 (18.8) | |
| T3 | 108 | 95 (88.0) | 13 (12.0) | |
| T4 | 22 | 19 (86.4) | 3 (13.6) | |
| Perineural invasion | 0.452 | |||
| Negative | 89 | 76 (85.4) | 13 (14.6) | |
| Positive | 58 | 52 (89.7) | 6 (10.3) | |
| Lymphovascular emboli | 0.553 | |||
| Negative | 116 | 102 (87.9) | 14 (12.1) | |
| Positive | 31 | 26 (83.9) | 5 (16.1) | |
| Lymph node | ||||
| . | 0.521 | |||
| Negative | 72 | 64 (88.9) | 8 (11.1) | |
| Positive | 75 | 64 (85.3) | 11 (14.7) | |
| Microsatellite status | 0.025 | |||
| MSS+MSI−L | 126 | 113 (89.7) | 13 (10.3) | |
| MSI-H | 21 | 15 (71.4) | 6 (28.6) | |
aBetween well+moderately vs. poorly+mucinous
bBetween T1 + T2 vs. T3 + T4