Figure 3.

Activity of compound 9029936 against biofilm formation by C. dubliniensis. C. dubliniensis isolate 12-1762 cells were grown in (A) GlcNAc or (B) Spider media to assess biofilm formation. The compound was tested in serial 2-fold dilutions with concentrations ranging from 40 to 0.078 μM, with appropriate positive and negative controls. Results are shown as mean percent biofilm inhibition compared to control biofilms (in the absence of compound) as determined by the Crystal violet biomass assay for multiple technical replicates from several independent experiments, error bars indicate standard deviations.