Table 2.

Fractional inhibitory concentration indices from drug combination assays.

Drug combinations	Biofilm inhibition	Pre-formed biofilms	Planktonic
9029936 + Fluconazole	Indifference (FICI = 1.8)	Indifference (FICI = 1.625)	Indifference (FICI = 1.187)
9029936 + Amphotericin B	Indifference (FICI = 1.06)	Indifference (FICI = 1.02)	Indifference (FICI = .6875)
9029936 + Caspofungin	Indifference (FICI = 1.3125)	Synergy (FICI = .4082)	Indifference (FICI = 1.328)

Compound 9029936 was assessed in combination with conventional antifungal drugs to determine inhibitory effects on C. albicans strain SC5314 planktonic growth, biofilm formation, and against preformed biofilms.