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. 2018 Jul 10;9:1485. doi: 10.3389/fimmu.2018.01485

Figure 5.

Figure 5

Association between serum expression of miR-503-5p, miR-34a-5p and miR-34a-3p with skin histopathological aGvHD incidence, overall clinical aGvHD grade and overall survival. (A) Scatterplots demonstrating miR-503-5p, miR-34a-5p, and miR-34a-3p expression (mean and SEM) in serum samples at Day 28 post-HSCT according to skin aGvHD stage/overall aGvHD grade. Significance was determined using the Student’s t-test. (B) Receiver operator characteristic (ROC) curves detailing area under the curve (AUC) and p-value significance for miR-503-5p, miR-34a-5p, and miR-34a-3p with incidence of skin aGvHD/clinical aGvHD. (C) Kaplan–Meier survival curves for OS, based on dichotomized miR-503-5p expression. p-Values were calculated using the Log-Rank test. (D) ROC curve detailing AUC and p-value significance for miR-503-5p and OS.