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Nec-1 ameliorates surgery-induced synaptic damage in D-Gal-induced aged mice. (A–C) Represents qPCR assay for GluA1, GluA2 and NR2B, respectively. Data were expressed as the mean ± SEM (n = 6 per time point per group, two way ANOVA followed by Tukey’s multiple comparison test). #P < 0.05, compared with control group; *P < 0.05, in comparison between Sur+DMSO and Sur+Nec1 groups. (D). Representative images of Doublecortin (DCX) staining (yellow) in the dentate gyrus. Bar = 50 μm.
