Table 4. The hemodynamic parameters examined by left ventricular intubation in all the rats after intervention.
| Group | n | Body weight (g) | LVEDP (mmHg) | LVESP (mmHg) | +dp/dt max (mmHg/s) | −dp/dt max (mmHg/s) |
|---|---|---|---|---|---|---|
| Benazepril HCL | 20 | 370.1 ± 36.9 | 16.21 ± 1.95 | 145.21 ± 4.41 | 5055 ± 389 | 5019 ± 489 |
| Sham operation | 20 | 386.5 ± 40.1 | 5.23 ± 0.82 | 129.63 ± 4.33 | 6010 ± 367 | 6401 ± 609 |
| CHF model | 181 | 360.0 ± 25.3 | 36.25 ± 1.452 | 169.86 ± 6.692 | 4668 ± 3592 | 4023 ± 6542 |
| Low-dose | 191 | 375.2 ± 20.1 | 18.12 ± 1.653 | 146.15 ± 5.233 | 4956 ± 4543 | 4401 ± 4213 |
| High-dose | 20 | 379.2 ± 30.5 | 8.82 ± 1.623 | 120.53 ± 6.013 | 5339 ± 4013 | 4989 ± 4553 |
The quantitative data are shown as the means ± S.D. Abbreviations: +dp/dtmax, LV maximal first derivative of pressure rising over time; –dp/dtmax, LV maximal first derivative of pressure dropping over time.
1Two rats died in the CHF model group, and one rat died in the CHF + low-dose AS-IV group.
2P<0.01 compared with the sham operation.
3P<0.01 compared with the CHF model.