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Glial cells from brain specimens were observed in the absence (upper) and presence of antibodies to CREB3L1 (middle) and PTN (down). The CREB3L1- and PTN-positive cells were shown in a brown color under a light microscope (×200), respectively. There were statistical differences in the CREB3L1 and PTN staining cell counts between any two groups (all P<0.05, n=5).
