Table 4.
Characteristics immediately after return of spontaneous circulation (ROSC).
| Early transfusion (n = 22) | Crystalloid (n = 22) | ||||
|---|---|---|---|---|---|
| Time to ROSC | (s) | 163 | (162–199) | 164 | (129–198) |
| Epinephrine | (No. of animals with 1/3/7 doses) | 20/1/1 | 22/0/0 | ||
| ctHb | (g/dl) | 4.6 | (3.8–6.7) | 5.6 | (4.3–6.5) |
| Hct | (%) | 14.7 | (12.2–20.9) | 17.7 | (13.9–20.3) |
| SaO2 | (%) | 99.5 | (99.8–100) | 100 | (99.3–100) |
| PaCO2 | (mm Hg) | 46.8 | (32.6–54.6) | 39.5 | (35.1–49.1) |
| PaO2 | (mm Hg) | 172 | (148–198.3) | 200.5* | (174.8–255.5) |
| pH | 7.00 | (6.85–7.09) | 7.03 | (6.93–7.11) | |
| BE | (mmol/l) | −18.9 | (−24.3 to −16.6) | −18.7 | (−21.3 to −16.5) |
| Glucose | (mg/dl) | 195 | (152–257) | 199 | (150–241) |
| Lactate | (mmol/l) | 14.9 | (14.2–17.0) | 13.3** | (7.0–15.0) |
| K+ | (mmol/l) | 6.8 | (6.0–7.6) | 5.9† | (5.1–6.9) |
| Na+ | (mmol/l) | 139 | (136–141) | 138 | (137–141) |
| Ca2+ | (mmol/l) | 1.34 | (1.11–1.41) | 1.33 | (1.30–1.39) |
| HR | (Beats/min) | 174 | (149–224) | 198 | (180–224) |
| MeanBP | (mmHg) | 37.9 | (26.1–49.3) | 47.0‡ | (39.3–58.8) |
| Paw | (cm H2O) | 5.0 | (4.8–5.1) | 4.9a | (4.8–5.0) |
| Pe | (cm H2O) | 11.0 | (8.6–14.4) | 9.5a | (8.2–14.5) |
| CVP | (mmHg) | 5.7 | (4.9–6.8) | 5.6 | (4.9–7.0) |
| Temp. | (°C) | 39.1 | (39.0–39.3) | 39.1 | (38.9–39.3) |
| Vt | (ml/kg) | 16.1 | (9.9–30.4) | 19.6 | (13.5–25.8) |
| Early transfusion (n = 17) | Crystalloid (n = 16) | ||||
| Transfused volume | (ml) | 4.0 | (3.0–8.0) | 6.0 | (3.6–8.8) |
| Transfused volume/Extracted blood | (%) | 10.5 | (6.9–19.6) | 14.1 | (7.8–25.5) |
Values are presented as median (IQR); BP, blood pressure, Paw, mean airway pressure, Pe, mean esophagus pressure, CVP, central venous pressure, Vt, tidal volume;
*
p = 0.007,
**
p = 0.004,
†
p = 0.014,
‡
p = 0.037;
a
n = 21.