Table 5.
Significant differences during monitoring period and characteristics at 4 h after ROSC.
| 1 h after ROSC | Early transf. (n = 20) | Crystalloid (n = 21) | |||||
|---|---|---|---|---|---|---|---|
| Lactate | (mmol/l) | 12.5 | (11.5–14.1) | 10.4* | (5.3–13.1) | ||
| 2 h after ROSC | Early transf. (n = 20) | Crystalloid with late volume infusion 1 h after ROSC | |||||
| Blood (n = 10) | Sodium chloride 0.9% (n = 11) | ||||||
| MeanBP | (mmHg) | 31.9 | (25.5–38.3) | 41.5** | (36.2–46.4) | 32.8 | (28.2–36.3) |
| 4 h after ROSC | Early transf. (n = 19) | Crystalloid with late volume infusion 1 h after ROSC | |||||
| Blood (n = 10) | Sodium chloride 0.9% (n = 11) | ||||||
| ctHb | (g/dl) | 4.4 | (3.7–6.0) | 5.7 | (4.9–6.1) | 5.2c | (4.0–7.2) |
| Hct | (%) | 14 | (11.8–18.9) | 18.1 | (18.7–19.3) | 16.3c | (13–22.4) |
| SaO2 | (%) | 94.6 | (90.3–99.4) | 92.7b | (89.9–94.2) | 95.8c | (93.3–97.6) |
| PaCO2 | (mm Hg) | 40.6 | (39.1–43.8) | 43.0 | (40.7–46.1) | 40.4c | (38.6–42.5) |
| PaO2 | (mm Hg) | 75.6 | (65.2–91.2) | 76.6 | (66.7–87.4) | 77.2c | (71.3–83.8) |
| pH | 7.23 | (7.11–7.29) | 7.29 | (7.18–7.35) | 7.29c | (7.13–7.38) | |
| BE | (mmol/l) | −8.6 | (−16.7 to −5.6) | −5.2 | (−10.7 to −3.2) | −6.5c | (−15.0 to −0.9) |
| Glucose | (mg/dl) | 95 | (81–122) | 99 | (84–115) | 98c | (72–125) |
| Lactate | (mmol/l) | 4.7 | (3.2–11.7) | 2.7 | (2.1–6.1) | 3.6c | (1.8–6.7) |
| K+ | (mmol/l) | 5.4 | (4.5–5.9) | 4.9 | (4.5–5.9) | 5.5c | (4.8–6.4) |
| Na+ | (mmol/l) | 138 | (136–139) | 137 | (136–138) | 137c | (134–139) |
| Ca2+ | (mmol/l) | 1.45 | (1.41–1.55) | 1.38 | (1.35–1.51) | 1.41c | (1.36–1.54) |
| HR | (Beats/min) | 252 | (228–264) | 243 | (227–258) | 222 | (192–246) |
| MeanBP | (mmHg) | 31.2a | (21.7–41.7) | 37.3 | (33.8–41.2) | 39.2 | (28.1–43.0) |
| Paw | (cm H2O) | 4.9 | (4.8–5.0) | 4.9b | (4.8–5.1) | 4.8 | (4.7–4.9) |
| Pe | (cm H2O) | 5.4 | (4.1–8.2) | 5.4b | (4.1–7.7) | 6.8 | (4.1–8.2) |
| CVP | (mmHg) | 4.6 | (3.6–6.3) | 4.8 | (4.1–5.8) | 5.5 | (4.5–7.6) |
| Temp. | (°C) | 39.2 | (39.0–39.4) | 39.3 | (39.2–39.4) | 39.2 | (39.1–39.2) |
| PIP | (cm H2O) | 16 | (13–17) | 15 | (15–17) | 14 | (13 −15) |
| Vt | (ml/kg) | 8.2 | (6.7–10.2) | 9.0b | (8.0–10.6) | 8.7 | (7.1–8.9) |
| FiO2 | [%] | 23 | (21–25) | 23b | (22–27) | 23 | (22–25) |
| Dopamine (cumulative dose) | (mg/kg) | 3.2 | (2.9–3.9) | 3.3 | (3.0–3.5) | 3.5 | (3.1–3.6) |
Values are presented as median (IQR); HR, heart rate; BP, blood pressure; Paw, mean airway pressure; Pe, mean esophagus pressure; CVP, central venous pressure; PIP, inspiratory pressure; Vt, tidal volume;
*
p = 0.007,
**
p = 0.006;
a
n = 18,
b
n = 9,
c
n = 10.