Table 2.
Distribution of SNPs among all 480 MG patients without any subgroup distinction and 487 controls.
| SNPs | MAF | Genotypes | Genotype frequencies | P-value | |||
|---|---|---|---|---|---|---|---|
| MG | HC | MG | HC | Codominant | Additive | ||
| rs2107356 | 0.38 | 0.37 | CC | 174 (37.6) | 200 (41.3) | 0.46 | 0.43 |
| CT | 222 (48.0) | 214 (44.2) | |||||
| TT | 67 (14.5) | 70 (14.5) | |||||
| rs1805010 | 0.5 | 0.48 | GG | 127 (26.7) | 135 (27.7) | 0.71 | 0.42 |
| GA | 222 (46.7) | 233 (47.8) | |||||
| AA | 126 (26.5) | 119 (24.4) | |||||
| rs1805011 | 0.07 | 0.08 | AA | 409 (86.3) | 410 (84.2) | 0.51 | 0.52 |
| CA | 62 (13.1) | 75 (15.4) | |||||
| CC | 3 (0.6) | 2 (0.4) | |||||
| rs1805015 | 0.07 | 0.08 | TT | 409 (86.3) | 409 (84.0) | 0.26 | 0.49 |
| CT | 62 (13.1) | 77 (15.8) | |||||
| CC | 3 (0.6) | 1 (0.2) | |||||
| rs1801275 | 0.19 | 0.15a | AA | 305 (64.8) | 348 (71.5) | 0.048 | 0.015 |
| GA | 156 (33.1) | 131 (26.9) | |||||
| GG | 10 (2.1) | 8 (1.6) | |||||
| rs8832 | 0.45 | 0.42 | AA | 146 (30.7) | 157 (32.4) | 0.24 | 0.18 |
| GA | 233 (49.0) | 250 (51.5) | |||||
| GG | 96 (20.2) | 78 (16.1) | |||||
a
MG vs. HC, P = 0.036, OR = 1.293 95%CI (1.017–1.643), PBon = 0.216.