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Effect of RES on steroid metabolism by MDA-MB-231 and MCF-7 cells. MDA-MB-231 cells were incubated with (A) 100 nM DHEA or (B) 100 nM E1 as a hormone precursor in the presence and absence of 100 μM RES for 48 h. MCF-7 cells were incubated with (C) 100 nM DHEA or (D) 100 nM E1 as a hormone precursor in the presence and absence of 100 μM RES for 48 h. All data represent the means ± SD of three independent biological replicates.∗P < 0.05.
