Table 3.
Timing of CPT initiation, duration of therapy, reasons for discontinuation and contra-use among HIV/AIDS patients at JH and DRH, from September 2015 to August 2016.
| Indicator variables | JH (%) | DRH (%) | Overall (%) | |
|---|---|---|---|---|
| Timing of CPT initiation | CPT before ART (Weeks) | 168 (55.1) | 100 (39.8) | 268 (48.2) |
| <2 | 58 (34.5) | 27 (27.0) | 85 (31.7) | |
| 2 | 82 (48.8) | 12 (12.0) | 94 (35.1) | |
| >2 | 28 (16.7) | 61 (61.0) | 89 (33.2) | |
| CPT and ART simultaneously | 125 (41.0) | 78 (31.1) | 203 (36.5) | |
| CPT after ART (weeks) | 12 (3.9) | 73 (29.1) | 85 (15.3) | |
| <2 | 1 (8.3) | 9 (12.3) | 10 (11.8) | |
| 2 | 4 (33.3) | 2 (2.7) | 6 (7.1) | |
| >2 | 7 (58.3) | 62 (84.9) | 69 (81.2) | |
| Duration on CPT (Months) | <1 | 38 (12.5) | 36 (14.3) | 74 (13.3) |
| 1–3 | 103 (33.8) | 87 (34.7) | 190 (34.2) | |
| 3–6 | 55 (18.0) | 23 (9.2) | 78 (14.0) | |
| >6 | 109 (35.7) | 105 (41.8) | 214 (38.5) | |
| Reasons for discontinuation | CD4 > 350 cells/mm3 | 71 (49.3) | 44 (46.3) | 115 (48.1) |
| Severe allergic reactions | 14 (9.7) | 12 (12.6) | 26 (10.9) | |
| First trimester of pregnancy | 2 (1.4) | 1 (1.1) | 3 (1.3) | |
| Not documented | 57 (39.6) | 38 (40.0) | 95 (39.7) | |
| Subtotal | 144 (47.2) | 95 (37.8) | 239 (43.0) | |
| Contra-use | Sulfa allergy | 2 (9.1) | 2 (13.3) | 4 (10.8) |
| Renal insufficiency | 6 (27.3) | 1 (6.7) | 7 (18.9) | |
| First trimester of pregnancy | 2 (9.1) | 1 (6.7) | 3 (8.1) | |
| Severe anemia | 6 (27.3) | 5 (33.3) | 11 (29.7) | |
| Severe neutropenia | 4 (18.2) | 4 (26.7) | 8 (21.6) | |
| Sever thrombocytopenia | 1 (4.5) | 2 (13.3) | 3 (8.1) | |
| Subtotal | 22 (7.21) | 15 (5.97) | 37 (6.65) | |
JH, Jugel Hospital; DRH, Dilchora Referral Hospital; CPT, cotrimoxazole prophylactic therapy; ART, antiretroviral therapy.