Skip to main content
. 2018 Jun 1;8(6):964–980.

Figure 5.

Figure 5

GOLM1 targeting of MMP13 modulates the EMT process in cervical cancer. A. Representative images showing the associations between GOLM1 expression, MMP13 and EMT markers (Vimentin and E-cadherin) in cervical cancer samples. B-E. The percentage scoring of EMT marker (Vimentin and E-cadherin) expression in either GOLM1 low or high expression groups, and in either MMP13 low or high expression groups from cervical cancer samples. F. Morphological changes resulting from MMP13 overexpression in SiHa cells and MMP13-deficient Ca-Ski cells. G-I. Examination of EMT marker (E-cadherin, N-cadherin, Vimentin and TWIST1) expression in MMP13-overexpressing SiHa cells and MMP13 low expressing Ca-Ski cells by qPCR and western blotting assay. J. Comparison of EMT marker (E-cadherin, N-cadherin, Vimentin and TWIST1) expression between GOLM1 single overexpressing and GOLM1/shMMP13 SiHa cells. K. Comparison of EMT marker (E-cadherin, N-cadherin, Vimentin and TWIST1) expression between GOLM1 single down-expressing and shGOLM1/pLV-MMP13 Ca-SKi cells.