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The overall schematic design of the study. A. Starting the study with a randomized clinical trial to assess the add-on therapeutic effect of BENC on GC patients. B. An virtual study was conducted to explore the mechanism of BENC action on GC cells in the assistance of bioinformatic analysis tools. C. Further validation of the predicted cellular functional and related signaling impacts of BENC on GC cells using in vitro and in vivo assays.
