Figure 4.

MiR-125b-SIRT6 axis affects the cell migration of HCC cells. A. The effect of miR-125b on the migration of HepG2 and Sk-hep-1 cell lines. A representative photograph from three independent experiments is shown one. The plot shows the results of wound healing assay as mean ± SD of open wound area. Statistical analysis was performed using t-test. B. The effect of SIRT6 on the migration of HepG2 and Sk-hep-1 cell lines. C. The cell migration ability of 125b overexpression HepG2 and Sk-hep-1 cell lines upon SIRT6 transfection.