Table 2.

Metabolic variables in rats infused with IR insulin without coinfusion of glucose

	IR Insulin Only
Body wt (BW), g
Beginning	412.5 ± 6.0
Final	433.1 ± 7.6*
Kidney wt (KW), g
UNX	1.37 ± 0.02
Remaining	1.63 ± 0.06*
KW/BW
Beginning	0.0033 ± 0.0001
Final	0.0037 ± 0.0001*
Blood glucose, mmol/l
Control	7.3 ± 0.3
Insulin	7.4 ± 0.2
Plasma insulin, µU/ml
Control	7.01 ± 2.95
Insulin	14.60 ± 9.98
GFR, ml/min
Control	1.70 ± 0.10
Insulin	1.76 ± 0.13
Food intake, g/day
Control	16.5 ± 2.7
Insulin	19.2 ± 2.0
Water intake, ml/day
Control	5 ± 1
Insulin	7 ± 3
Plasma protein, g/dl
Control	6.2 ± 0.1
Insulin	6.3 ± 0.1
Hematocrit, %
Control	38 ± 1
Insulin	36 ± 1

Data are means ± SE; n = 6 rats per group.

^*P < 0.05 vs. beginning weight.