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. 2017 Oct 13;314(1):H105–H113. doi: 10.1152/ajpheart.00524.2017

Table 3.

Flow-mediated dilation, microparticles, monocyte-platelet aggregates, adhesion molecules, serum amyloid A, and C-reactive protein data before and after each 4-day condition

CON Diet
LC Diet
LC + Ex Diet
P Value
Pre Post Pre Post Pre Post Interaction Main effect
Baseline diameter, mm 0.39 ± 0.07 0.41 ± 0.09 0.39 ± 0.06 0.40 ± 0.06 0.40 ± 0.06 0.40 ± 0.07 0.15 0.11
Peak diameter, mm 0.42 ± 0.07 0.44 ± 0.08 0.42 ± 0.06 0.44 ± 0.07 0.43 ± 0.06 0.44 ± 0.06 0.33 0.11
Time to peak, s 51.3 ± 35.3 50.0 ± 26.7 51.1 ± 27.1 47.2 ± 30.4 44.6 ± 36.9 60.1 ± 47.1 0.48 0.67
Platelet microparticles, microparticles/μl 42.1 ± 26.5 46.1 ± 31.7 33.2 ± 30.8 33.9 ± 21.5 50.8 ± 20.0 28.8 ± 25.6 0.07 0.34
Total monocyte-platelet aggregates, cells/μl 77.5 ± 21.7 95.5 ± 22.7 80.2 ± 20.5 92.7 ± 27.9 77.3 ± 20.0 87.1 ± 19.0 0.15 <0.01
Monocyte-platelet aggregates, % 29.8 ± 5.5 31.3 ± 5.5 31.0 ± 6.4 32.7 ± 5.4 31.0 ± 6.4 31.3 ± 7.8 0.78 0.08
C-reactive protein, mg/l 8.0 ± 8.3 7.9 ± 8.5 5.3 ± 4.9 8.2 ± 8.4 7.3 ± 7.2 9.3 ± 11.4 0.12 0.29
Serum amyloid A, mg/l 5.7 ± 4.2 6.4 ± 4.3 3.9 ± 2.5 5.3 ± 5.6 5.3 ± 3.4 5.1 ± 4.2 0.72 0.30
ICAM-1, ng/ml 461 ± 89 478 ± 83 368 ± 111 402 ± 77 389 ± 102 422 ± 89 0.44 0.19
VCAM-1, ng/ml 392 ± 249 441 ± 255 320 ± 208 395 ± 217 389 ± 252 400 ± 248 0.48 0.06

Data are means ± SD; n = 11 for flow-mediated dilation; n = 9 for microparticles; n = 11 for monocyte platelet aggregates, adhesion molecules, serum amyloid A, and C-reactive protein. CON diet, control low-fat moderate-carbohydrate diet; LC diet, low-carbohydrate diet; LC + Ex diet, low-carbohydrate diet plus postmeal walking; Pre and Post, before and after each 4-day condition, respectively.