Table 3.
Flow-mediated dilation, microparticles, monocyte-platelet aggregates, adhesion molecules, serum amyloid A, and C-reactive protein data before and after each 4-day condition
CON Diet |
LC Diet |
LC + Ex Diet |
P Value |
|||||
---|---|---|---|---|---|---|---|---|
Pre | Post | Pre | Post | Pre | Post | Interaction | Main effect | |
Baseline diameter, mm | 0.39 ± 0.07 | 0.41 ± 0.09 | 0.39 ± 0.06 | 0.40 ± 0.06 | 0.40 ± 0.06 | 0.40 ± 0.07 | 0.15 | 0.11 |
Peak diameter, mm | 0.42 ± 0.07 | 0.44 ± 0.08 | 0.42 ± 0.06 | 0.44 ± 0.07 | 0.43 ± 0.06 | 0.44 ± 0.06 | 0.33 | 0.11 |
Time to peak, s | 51.3 ± 35.3 | 50.0 ± 26.7 | 51.1 ± 27.1 | 47.2 ± 30.4 | 44.6 ± 36.9 | 60.1 ± 47.1 | 0.48 | 0.67 |
Platelet microparticles, microparticles/μl | 42.1 ± 26.5 | 46.1 ± 31.7 | 33.2 ± 30.8 | 33.9 ± 21.5 | 50.8 ± 20.0 | 28.8 ± 25.6 | 0.07 | 0.34 |
Total monocyte-platelet aggregates, cells/μl | 77.5 ± 21.7 | 95.5 ± 22.7 | 80.2 ± 20.5 | 92.7 ± 27.9 | 77.3 ± 20.0 | 87.1 ± 19.0 | 0.15 | <0.01 |
Monocyte-platelet aggregates, % | 29.8 ± 5.5 | 31.3 ± 5.5 | 31.0 ± 6.4 | 32.7 ± 5.4 | 31.0 ± 6.4 | 31.3 ± 7.8 | 0.78 | 0.08 |
C-reactive protein, mg/l | 8.0 ± 8.3 | 7.9 ± 8.5 | 5.3 ± 4.9 | 8.2 ± 8.4 | 7.3 ± 7.2 | 9.3 ± 11.4 | 0.12 | 0.29 |
Serum amyloid A, mg/l | 5.7 ± 4.2 | 6.4 ± 4.3 | 3.9 ± 2.5 | 5.3 ± 5.6 | 5.3 ± 3.4 | 5.1 ± 4.2 | 0.72 | 0.30 |
ICAM-1, ng/ml | 461 ± 89 | 478 ± 83 | 368 ± 111 | 402 ± 77 | 389 ± 102 | 422 ± 89 | 0.44 | 0.19 |
VCAM-1, ng/ml | 392 ± 249 | 441 ± 255 | 320 ± 208 | 395 ± 217 | 389 ± 252 | 400 ± 248 | 0.48 | 0.06 |
Data are means ± SD; n = 11 for flow-mediated dilation; n = 9 for microparticles; n = 11 for monocyte platelet aggregates, adhesion molecules, serum amyloid A, and C-reactive protein. CON diet, control low-fat moderate-carbohydrate diet; LC diet, low-carbohydrate diet; LC + Ex diet, low-carbohydrate diet plus postmeal walking; Pre and Post, before and after each 4-day condition, respectively.