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Average mean arterial pressure (top) and hindlimb resistance (bottom) responses (n = 6) during free-flow exercise, metaboreflex threshold, and maximal metaboreflex activation in control (○) and α1-adrenergic blockade (●) experiments in normal animals (left) and after induction of heart failure (right). *P < 0.05 vs. mean arterial pressure or hindlimb resistance at the previous setting in the same experiment. †P < 0.05 vs. control. ‡P < 0.05 vs. normal.
