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. 2018 Jun 25;115(28):7392–7397. doi: 10.1073/pnas.1703029115

Fig. 3.

Fig. 3.

Ectopic miR-34a suppresses breast cancer cell proliferation while inducing apoptosis and cell cycle arrest at S phase. (A) At 10 d after Dox treatment, HCC1806 cells expressing miR-34a were replated to determine the effect of ectopic miR-34a expression on cell proliferation. (B) At 10 d after Dox exposure, the levels of miR-34a were detected by qRT-PCR. (C and D) The effects of ectopic miR-34a on apoptosis (C) and the cell cycle (D) were determined at 10 d after Dox exposure; Dox(−) served as the control. *P < 0.05.