Table 8.
Results of PCP Salvage Reirradiation.
Author | Number of Patients | Years of Treatment | TD (Gy) | Equipment Used | Percent Receiving ADT | Median FU (Months) | Endpoint | Results (%) |
---|---|---|---|---|---|---|---|---|
Zilli et al 19 | 14a | 2003-2008 | 44-72 + 18-25h | Unspecified | 79 | 94 | 5 years bDFS | 35.7 |
Vavassori et al 20 | 6b | 2007-2008 | 30 | CyberKnife | 60 | 11.2 | bDFS | 40 |
Zerini et al 21 | 32c | 2008-2013 | 25-30 | Saturno 43, Clinac 600, Clinac 2100, RapidArc, Vero, CyberKnife | 34 | 21.3 | NED | 40.6 |
Fuller et al 22 | 29d | 2009-2014 | 34 | CyberKnife | 0 | 24 | 2 years bDFS | 82 |
Janoray23 | 11e | 2011-2014 | 36.25 | CyberKnife | 9 | 11.7 | 1 year bDFS | 85.7 |
Mbeutcha24 | 18f | 2011-2015 | 35 | CyberKnife | 55.6 | 14.5 | bNED | 55.6 |
Miszczyk et al | 38g | 2012-2017 | 18-36.25 | CyberKnife | 55.3 | 14.4 | NED LC | 68.4 86.8 |
Abbreviations: ADT, androgen deprivation therapy; bDFS, biological disease-free survival; LC, local control; FU, follow-up; NED, non-evidence of disease; PCP, prostate cancer patients; TD, total dose.
aModalities of treatment used during prior treatment: 12 EBRT, 2 EBRT + BT boost.
bModalities of treatment used during prior treatment: 6 EBRT.
cModalities of treatment used during prior treatment: 10 RT, 22 RP + RT, including 29 cases of EBRT and 3 cases of BT.
dModalities of treatment used during prior treatment: 28 EBRT, 1 125I BT.
eModalities of treatment used during prior treatment: 11 EBRT.
fModalities of treatment used during prior treatment: 18 EBRT.
gModalities of treatment used during prior treatment: 34 EBRT, 1 BT, 3 EBRT + BT boost.
fBT/CK boost.