Table 4.
Chinese herbal medicine for functional dyspepsia: summary of findings for the main comparison.
| Chinese herbal medicine compared with pharmacotherapy for functional dyspepsia | ||||
|---|---|---|---|---|
|
Population:
Patients with functional
dyspepsia Intervention: Chinese herbal medicine Comparison: Pharmacotherapy Settings: Any | ||||
| Outcomes | Illustrative comparative risks (95% CI) | Relative effect (95% CI) |
Participants, n (studies, n) | |
| Assumed risk | Corresponding risk | |||
| Alleviation of global dyspeptic symptoms | Pharmacotherapy | Modified Xiao Yao San | OR: 3.53 (2.32, 5.36) | 649 (5) |
| 694 per 1000 | 890 per 1000 | |||
| Alleviation of global dyspeptic symptoms | Prokinetic agents | Xiang Sha Liu Jun Zi decoction | OR: 3.29 (1.99, 5.43) | 507 (7) |
| 740 per 1000 | 934 per 1000 | |||
| Chinese herbal medicine + pharmacotherapy compared with pharmacotherapy for functional dyspepsia | ||||
|
Population:
Patients with functional
dyspepsia Intervention: Chinese herbal medicine + pharmacotherapy Comparison: Pharmacotherapy Settings: Any | ||||
| Outcomes | Illustrative comparative risks (95% CI) | Relative effect (95% CI) |
Participants, n (studies, n) | |
| Assumed risk | Corresponding risk | |||
| Pharmacotherapy | CHM + pharmacotherapy | |||
| Alleviation of global dyspeptic symptoms | Pharmacotherapy | Modified Xiao Yao San + pharmacotherapy | OR: 4.71 (2.69, 8.25) | 423 (6) |
| 705 per 1000 | 917 per 1000 | |||
| Alleviation of global dyspeptic symptoms | Mosapride | Shu Gan Jie Yu capsule + mosapride | OR: 3.57 (2.53, 5.05) | 918 (9) |
| 678 per 1000 | 880 per 1000 | |||
Alleviation of global or individual dyspeptic symptoms is measured by the Gastrointestinal Symptom Rating Scale (GSRS) or other standardized scales. GSRS measures patient reported dyspeptic symptom severity on a four-point Likert scale (symptom free, marked improvement, slight improvement, and no improvement).
CHM, Chinese herbal medicine; OR, odds ratio; CI, confidence interval.