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. 2018 Jul 1;17:1533033818783879. doi: 10.1177/1533033818783879

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© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Partial response (PR) of a primary tumor to simultaneous integrated boost-proton beam therapy (SIB-PBT). (A) Definition of target volumes depending on the proximity of gastrointestinal structures, (B) pretreatment CT scans showing the primary tumor (arrow), (C) the patient underwent SIB-PBT, and (D) CT scans 3 months after SIB-PBT demonstrating PR of the primary tumor (arrow). CT indicates computed tomography; GTV, gross tumor volume; ITV, internal target volume; PTV, planning target volume.