Figure 1.

Effect of citalopram on clinical and psychological measures.

(a) There is small but statistically insignificant reduction in GDS over the 1-month study; (b) platelet [5-HT] shows a significant reduction of the study period (n = 7, p < 0.01, Friedman test); (c) there is significant correlation between the change in GDS during treatment and MMSE, although mean MMSE remains stable over the study period; (d) n = 19, R² = 0.27, p = 0.02, Pearson’s correlation; (e) and (f) both plasma Na⁺ and Hb concentrations remained stable over the study period, respectively.

GDS, Geriatric Depression Scale; Hb, haemoglobin; MMSE, Mini Mental State Examination Score; Na⁺, sodium.