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. 2018 Jul 1;17:1533033818783450. doi: 10.1177/1533033818783450

Table 6.

Prognostic Factors of 2-Year Progression-Free Survival; Univariate Analysis and Multivariate Analysis.

Prognostic Factor All Patients (n = 150) SBRT Alone (n = 28) SBRT + TACE (n = 122)
Number 2-Year OS (%) UVA, P Value MVA, P Value Number 2-Year OS (%) UVA, P Value MVA, P Value Number 2-Year OS (%) UVA, P Value MVA, P Value
Age, years ≧75 73 35.9 .1027 16 63.6 .9466 57 30.7 .0643
<75 77 51.1 12 39.3 65 52.4
Gender Male 99 42 .825 17 24.5 .1219 82 44.1 .5285
Female 51 47.5 11 80.8 40 39.9
Performance status 0 128 40.9 .1242 21 40.1 .0826 107 40.9 .5434
1 or 2 22 68.7 7 100 15 57
CTP class A 127 46.6 .0936 23 52.3 .8956 104 45.3 .0484 .028
B 23 31.9 5 37.5 18 29.3
Viral infection HCV 109 39.7 .0025 .0017 18 58.2 .8181 91 36.7 .0017 .001
Non-HCV 41 56.3 10 38.6 31 62.4
BCLC stage 0 80 48.8 .2006 17 40.1 .4716 63 50 .0946
A 70 38.8 11 62.3 59 35
T stage T1 113 52.3 .001 .0203 24 50.9 .6021 89 52.3 <.0001 .012
T2 37 18.3 4 50 33 13.5
Greatest tumor dimensions ≧20 mm 63 42.5 .8397 12 49.1 .972 47 38.6 .8236
<20 mm 87 45.4 12 43 75 45.4
Tumor location Central 13 49.4 .32 4 33.3 .4061 9 40.6 .1224
Periferal 137 43.5 24 61.9 113 77.8
Diagnosis history Initial 36 62 .0194 .0153 13 72.9 .0396 23 56.6 .1365
Recurrence 114 38.7 15 28.4 99 39.6
Previous treatment (surgery) Yes 61 37.7 .0891 9 31.1 .0773 52 38.8 .256
No 89 48.9 19 59 70 46.1
Previous treatment (RFA/PEI) Yes 41 37.5 .1796 5 33.3 .2962 35 38.1 .2956
No 109 46.6 23 54.4 87 44.6
Adverse effects <Grade 3 122 46.4 .6421 23 48.8 .43 99 45.6 .3302
≧Grade 3 28 34.8 5 53.3 23 30.4
Combination with TACE Yes 28 49 .1889
No 122 42.9

Abbreviations: BCLC; Barcelona Clinic Liver Cancer; CTP; Child-Turcotte-Pugh; HCV; hepatitis C virus; MVA, multivariate analyses; OS, overall survival; PFS, progression-free survival; RFA/PEI; radiofrequency ablation/percutaneous ethanol injection; SBRT, stereotactic body radiotherapy; TACE, transcatheter arterial chemoembolization; UVA, univariate analyses.