Table 3.
Reported species-related expression and suggested physiological and pathophysiological relevance of pancreas aquaglyceroporins.
Aqua-glyceroporin | Cell type | Suggested physiological role | Suggested pathophysiological involvement |
---|---|---|---|
AQP3 | Absent in β-cells (m, r) | ||
AQP7 | β-cells (m, r) | Insulin secretion | Obesity |
TAG synthesis; uptake of glycerol | |||
Lipolysis; release of glycerol | |||
Regulation of β-cell size and number | |||
AQP9 | β-cells (r)∗ | ||
AQP10 | Undefined |
m, mouse; r, rat; ∗present in ± 10% of samples.