Fig. 2.

Co-administration of SAHA and veliparib synergistically increased PCa killing. PCa and non-malignant prostate epithelial cells were treated with increased doses of SAHA or veliparib alone or in combination at a constant ratio of 1:20 for 3 days. Representative crystal violet-stained cell images are shown (left). The cells were lysed with 1% SDS, and cell viability was measured by spectrometer as OD570 nm. Graph represents the mean cell viability ± SD of 3 independent experiments.* p < 0.05;**p < 0.01(co-treatment vs. SAHA or veliparib alone). a LNCaP. b C4–2. c VCaP. d CWR22Rv1. e PC-3. f DU145. g RWPE-1