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. 2018 Jul 16;37:153. doi: 10.1186/s13046-018-0810-7

Table 1.

Co-effect of SAHA and veliparib

Cell lines (SAHA: Veliparib) CI values (IC50)
LNCap (1:20) 0.86
C4–2 (1:20) 0.95
VCaP (1:20) 0.90
CWR22Rv1 (1:20) 0.85
PC-3 (1:20) 0.74
DU145 (1:20) 0.85
RWPE-1 (1:20) 1.05

IC50: Half maximal inhibitory concentration

CI value: Combination index value

CI < 1 indicates synergy; CI = 1 indicates addictivity; CI > indicates antagonism