Table 2.
Results in the SIR 3 and simulated data sets
| Type | Pneumonia on admission | Hospital-acquired pneumonia | |
|---|---|---|---|
| Estimated constant hazards in the data sets: | |||
| Infection hazard α01 | - | 0.0063 | |
| Discharge hazard w/o pneumonia α02 | 0.0671 | 0.0627 | |
| Death hazard w/o pneumonia α03 | 0.0076 | 0.0075 | |
| Discharge hazard with pneumonia α14 | 0.0279 | 0.0334 | |
| Death hazard with pneumonia α15 | 0.0084 | 0.0093 | |
| Results: | |||
| HR(death) | 1.11;1.24∗ | 1.00 (0.72,1.39) | 0.9 (0.6,1.34) |
| HR(discharge) | 0.42;0.53∗ | 0.44 (0.38,0.52) | 0.59 (0.49,0.72) |
| SHR(death) | 2.37 (1.72,3.26) | 3.44 (2.36,5.03) | |
| OR(death) | 2.64;2.34∗ | 2.66 (1.86,3.81) | 2.34 (1.54,3.54) |
| Simulated data: | |||
| Scenario 0: α01=0.05, α02=0.2,α14=0.1, α03=α15=0.05 | |||
| HR(death) | 1 | 1.00 (0.92,1.12) | 0.99 (0.91,1.09) |
| HR(discharge) | 0.5 | 0.50 (0.48,0.53) | 0.50 (0.47,0.53) |
| SHR(death) | 1.73 (1.59,1.93) | 3.24 (2.99,3.55) | |
| OR(death) | 2 | 2.01 (1.81,2.27) | 1.99 (1.77,2.26) |
| Scenario 1: α01=0.01, α02=α14=0.05, α03=α15=0.01 | |||
| HR(death) | 1 | 1.01 (0.90,1.15) | 1.00 (0.87,1.15) |
| HR(discharge) | 1 | 1.00 (0.95,1.05) | 1.00 (0.94,1.06) |
| SHR(death) | 1.01 (0.9,1.17) | 1.98 (1.77,2.26) | |
| OR(death) | 1 | 1.01 (0.89,1.18) | 1.00 (0.89,1.15) |
| Scenario 2: α01=0.05, α02=α14=0.2, α03=0.05, α15=0.1 | |||
| HR(death) | 2 | 2.01 (1.86,2.22) | 1.98 (1.82,2.18) |
| HR(discharge) | 1 | 1.00 (0.95,1.06) | 1.00 (0.95,1.05) |
| SHR(death) | 1.84 (1.68,2.05) | 3.57 (3.26,3.92) | |
| OR(death) | 2 | 2.01 (1.81,2.27) | 1.99 (1.77,2.26) |
| Scenario 3: α01=0.05, α02=α14=0.2, α03=0.1, α15=0.075 | |||
| HR(death) | 0.75 | 0.75 (0.7,0.82) | 0.75 (0.67,0.86) |
| HR(discharge) | 1 | 1.00 (0.95,1.05) | 1.00 (0.93,1.08) |
| SHR(death) | 0.78 (0.72,0.86) | 1.50 (1.36,1.70) | |
| OR(death) | 0.75 | 0.75 (0.68,0.84) | 0.75 (0.66,0.86) |
| Scenario 4: α01=0.05, α02=0.2, α14=0.3, α03=α15=0.05 | |||
| HR(death) | 1 | 1.01 (0.91,1.16) | 0.99 (0.88,1.11) |
| HR(discharge) | 1.5 | 1.50 (1.42,1.57) | 1.50 (1.43,1.59) |
| SHR(death) | 0.71 (0.63,0.83) | 1.40 (1.27,1.58) | |
| OR(death) | 0.67 | 0.68 (0.60,0.80) | 0.66 (0.60,0.75) |
Upper part: Estimated hazards and results in the SIR 3 data set 95% confidence intervals are given in parenthesis. Lower part: Average results of 100 data sets with 10000 individuals per data set with empirical 95% confidence intervals in parenthesis. If applicable, the true HRs and ORs are given. The infection hazard α01 is only applicable for HAP. ∗: The values show the HRs computed with the estimated constant hazards. The first value corresponds to pneumonia on admission, the second to HAP