Table 3.
Univariable analysis of association between metal tolerance and antimicrobial resistance in clinical isolates of H. somni from feedlot cattle in Alberta (n = 63).
| Metal tolerance (MIC > 1 mM) | Resistant phenotypea | Odds ratio | 95% Confidence interval | P value |
|---|---|---|---|---|
| Copper | Oxytetracycline | 45.5 | 8.1–253.3 | <0.001 |
| Tylosin | 4.9 | 1.4–17.4 | 0.01 | |
| Neomycin | 7.9 | 0.8–83.3 | 0.08 | |
| Zinc | 54.0 | 6.4–452.6 | <0.001 | |
| Multidrug resistance | 14.5 | 3.9–54.8 | <0.001 | |
| Zinc | Oxytetracycline | 13 | 2.4–64.7 | 0.002 |
| Penicillin | 14.7 | 4.3–49.9 | <0.001 | |
| Neomycin | 3.8 | 0.4–38.8 | 0.19 | |
| Tylosin | 2.4 | 0.9–6.7 | 0.09 | |
| Copper | 54.0 | 6.4–452.6 | <0.001 | |
| Multidrug resistance | 7.6 | 2.4–24.3 | 0.001 |
a
Corresponding susceptible category was taken as reference category for calculating odds ratio.