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. 2018 Jul 16;49:63. doi: 10.1186/s13567-018-0556-4

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Mean S2 cDNA copy number and infectivity at viraemic peak. A S2 cDNA mean copy number at viraemic peak by tested serotype and vaccinated status. B Infectivity at viraemic peak, expressed as mean Log TCID₅₀/mL of blood titre by tested serotype and vaccinated status. Dotted line represents the classical threshold of 10³¹⁵⁵ TCID₅₀/mL required to allow BTV transmission to vector Culicoides. *For NV_BTV4, one animal had no detectable viraemia at all was excluded from calculation. Error bars represent standard deviation.