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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Sci Signal. 2018 May 1;11(528):eaam9095. doi: 10.1126/scisignal.aam9095

Figure 4. GML does not affect regulatory molecules involved in Arp2/3 complex activation.

Figure 4

(A) Western blotting analysis of active GTP-bound Rac1 and CDC42 was performed at the indicated times after restimulation of activated T cells in the presence of ethanol or GML. Top: Blots are representative of 3 independent experiments. Bottom: Normalized band intensity data are means ± SEM. (B and C) Western blotting analysis of total WASp, Arp2, ARPC3, and phosphorylated WASp Y290 was performed at the indicated times after restimulation of activated T cells treated with GML or ethanol. Blots (B) are representative of 3 independent experiments. Normalized band intensity data (C) are means ± SEM.