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. 2018 Jun 5;4:216–235. doi: 10.1016/j.isci.2018.06.001

Figure 8.

Figure 8

Model for rDNA Condensation Induced by Glucose Starvation

Upon glucose starvation, relaxed rDNA chromatin condenses to form higher order rDNA loops or rings (primary stage). Then, the rDNA loops twist and further condense into rDNA clusters (secondary stage). The condensin complex is loaded onto relaxed chromatin (possibly with other unknown factors) to catalyze rDNA condensation.