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Case study of consistent and inconsistent predictions. The backbone of DNA is marked as orange while protein is shown as brown. Mutation site is labeled as red along with the side chain of the wild-type residue. (A) The estrogen receptor DNA-binding domain bound to DNA (PDB: 1HCQ). (B) DNA complex of the Myb DNA-binding domain (PDB: 1MSE). (C) TN916 integrase n-terminal domain/DNA complex (PDB: 1TN9). (D) F Factor TraI Relaxase Domain bound to F oriT Single-stranded DNA (PDB: 2A0I)
