Fig. 2.

—Phylogenetic relationships and motif compositions of some representative MORC genes in plants and animals. The phylogenetic tree was reconstructed using some representative species based on the ML method implemented in RaxML-HPC2 through the online CIPRES Science Gateway website. For major nodes, ML bootstrap values >70% are labeled based on 1,000 replications. Motifs conserved across MORC proteins were identified through a MEME analysis and each motif composition is presented in supplementary figure S3, Supplementary Material online. Based on their highly conserved motif composition, we proposed a characteristic MORC domain that was marked in red box on the right.