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. Author manuscript; available in PMC: 2019 Apr 1.

Published in final edited form as: Pregnancy Hypertens. 2018 Feb 24;12:53–57. doi: 10.1016/j.preghy.2018.02.009

Table 3.

Associations between female fetal sex and immune markers in the first, second and postpartum periods

	First Trimester N=250	Second Trimester N=392	Postpartum N=591
	^a ^b Adj. OR (95% CI)	^a ^b Adj. OR (95% CI)	^a ^b Adj. OR (95% CI)
IFNγ	0.5, 0.3–0.8	1.0, 0.7–1.5	^c NA
IL1β	0.9, 0.6–1.3	1.5, 1.1–2.0	1.1, 0.9–1.4
IL4	1.0, 0.7–1.4	1.2, 0.9–1.6	1.1, 0.9–1.4
IL4r	0.9, 0.7–1.2	1.3, 1.1–1.6	1.1, 0.9–1.3
IL5	0.8, 0.5–1.1	1.4, 1.1–1.8	1.1, 0.9–1.4
IL8	0.8, 0.5–1.1	1.2, 0.9–1.5	1.0, 0.8–1.2
IL6	1.0, 0.8–1.4	1.1, 0.8–1.4	1.1, 0.9–1.3
IL10	0.9, 0.7–1.3	1.3, 1.1–1.7	1.2, 1.0–1.4
IL12	0.7, 0.5–1.0	1.3, 1.0–1.8	1.2, 0.9–1.6
MIF	0.9, 0.7–1.2	1.2, 0.9–1.5	0.8, 0.7–1.0
MIP	0.8, 0.6–1.1	1.2, 0.9–1.5	1.1, 0.9–1.3
TGFβ	1.0, 0.7–1.3	1.1, 0.9–1.4	1.1, 0.9–1.3
TNFβ	0.9, 0.5–1.5	1.7, 1.1–2.5	^c NA
TNFr	0.8, 0.6–1.1	1.1, 0.8–1.3	0.9, 0.8–1.1

^a

Cox regression was used to estimate effect size using a method described by Dinse et al. Details are in the methods section.

^b

Adjustments were made for race, age, gestational age at blood draw, smoking and BMI

^c

Excluded as >50% were below the LOD