Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug;24(8):991–1004. doi: 10.1261/rna.064386.117

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Steiman-Shimony et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article, published in RNA, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

FIGURE 2. — Coexpression and cotranscription of intronic miRNAs with their host genes. (A) Distribution of Jaccard index of host dependent TSSs for 638 intronic miRNAs over 54 cell lines, indicating little cotranscription of miRNA and host. (B) Distribution of the Jaccard index in A is independent of the number of cell lines in which data were available. Intronic miRNAs with TSS data were divided into three groups according to their Jaccard index for TSSs as follows: Jaccard index of 0 (left); Jaccard index above 0 and below 1 (center); Jaccard index of 1 (right). Box plots were made for each group showing the distribution of the number of cell lines in which each intronic miRNA had TSS data. It is clear that the low/high Jaccard indices are not due to small/large number of cell lines for which data were available. (C) Distribution of Jaccard index of coexpression of 149 intronic pre-miRNAs with their hosts over 28 cell lines based on pre-miRNA expression data from Landgraf et al. (2007), indicating little coexpression of miRNA and host. (D) Similarly, distribution of Jaccard index of coexpression of 829 intronic pre-miRNAs with their hosts over 14 cell lines based on miRNA expression data from miRmine (Panwar et al. 2017), also indicating little coexpression.