Fig. 1.

Effect of lettuce seed extract on sleep onset and sleep duration in mice treated with pentobarbital (42 mg/kg, i.p.). Control was just pentobarbital treated-mice group and pentobarbital was administered 40 min after oral administration of the lettuce seed extract. (A) Sleep latency of red and green lettuce seed extract. (B) Sleep latency of red and green romaine lettuce seed extract. (C) Sleep duration of red and green lettuce seed extract. (D) Sleep duration of red and green romaine lettuce seed extract. Each column represents the mean ± SE of the values obtained from 8 mice. Different letters mean significant differences (p < 0.05) among samples (Duncan’s multiple range test)