Fig. 5.

GLMOC regulated the MAPKs signaling pathway in LPS-induced RAW264.7 cells. The cells (8 × 10⁵ cells in a 60 mm dish) were pretreated 2 h with GLMOC or SA, and then LPS was treated for 30 min. The protein levels of p-p38, p38, p-ERK, ERK, p-JNK, JNK, and β-actin were determined by Western blot. Values represent mean ± SD. Different lowercase letters indicate significant differences at p < 0.05. GLMOC (50, 100, and 300 μg/mL), SA (10 μM), LPS (100 ng/mL)