Table 2.
Biochemical parameters at baseline, 3 months, and 6 months
| Parameter | Timepoint | Groupa | P value | |||
|---|---|---|---|---|---|---|
| C (n = 7) | M (n = 7) | M + PA (n = 7) | (Time, interaction) | |||
| Triglycerides (mg/dL) | Baseline | 116.3 ± 72.4 | 129.6 ± 89.7 | 113.0 ± 58.5 | 0.487 | 0.016 |
| 3 months | 162.3 ± 126.8 | 97.6 ± 49.6 | 71.9 ± 42.4 | |||
| 6 months | 113.6 ± 63.9 | 102.1 ± 10.4 | 83.6 ± 43.9 | |||
| Total cholesterol (mg/dL) | Baseline | 201.1 ± 19.0 | 200.9 ± 31.6 | 214.6 ± 42.4 | 0.32 | 0.591 |
| 3 months | 214.9 ± 24.2 | 202.7 ± 20.2 | 208.9 ± 46.8 | |||
| 6 months | 203.7 ± 16.1 | 194.4 ± 21.0 | 206.1 ± 36.8 | |||
| HDL cholesterol (mg/dL) | Baseline | 53.6 ± 8.2 | 61.4 ± 9.9 | 59.0 ± 14.7 | 0.281 | 0.495 |
| 3 months | 54.1 ± 13.5 | 56.9 ± 10.3 | 58.9 ± 13.3 | |||
| 6 months | 52.3 ± 10.5 | 58.3 ± 8.5 | 57.6 ± 15.2 | |||
| LDL cholesterol (mg/dL) | Baseline | 119.9 ± 15.7 | 105.1 ± 19.3 | 133.6 ± 45.2 | 0.165 | 0.331 |
| 3 months | 125.1 ± 17.8 | 109.7 ± 15.4 | 132.4 ± 48.7 | |||
| 6 months | 121.6 ± 15.8 | 103.7 ± 15.2 | 129.4 ± 45.1 | |||
| LCAT (U) | Baseline | 107.0 ± 13.7 | 103.0 ± 20.8 | 112.1 ± 26.6 | 0.395 | 0.223 |
| 3 months | 110.6 ± 17.0 | 98.5 ± 10.3 | 95.8 ± 19.5 | |||
| 6 months | 104.9 ± 15.3 | 109.5 ± 29.1 | 102.0 ± 25.0 | |||
| Glucose (mg/dL) | Baseline | 100.3 ± 11.7 | 103.0 ± 5.8 | 99.9 ± 7.2 | 0.163 | 0.097 |
| 3 months | 102.9 ± 9.5 | 97.6 ± 6.1 | 93.7 ± 4.5 | |||
| 6 months | 100.7 ± 10.8 | 88.0 ± 15.1 | 93.0 ± 6.8 | |||
| Insulin (μIU/mL) | Baseline | 4.9 ± 1.4 | 6.4 ± 3.1 | 9.4 ± 6.6 | 0.474 | 0.003 |
| 3 months | 6.4 ± 1.6 | 5.4 ± 2.4 | 7.5 ± 6.3 | |||
| 6 months | 7.0 ± 3.0 | 5.4 ± 2.1 | 6.8 ± 6.5 | |||
| HOMA-IR | Baseline | 1.2 ± 0.4 | 1.6 ± 0.8 | 2.3 ± 1.5 | 0.395 | 0.007 |
| 3 months | 1.6 ± 0.33 | 1.3 ± 0.6 | 1.8 ± 1.5 | |||
| 6 months | 1.7 ± 0.7 | 1.4 ± 0.6 | 1.6 ± 1.6 | |||
| SGOT (U/L) | Baseline | 24.6 ± 4.8 | 26.7 ± 10.8 | 28.9 ± 13.5 | 0.086 | 0.435 |
| 3 months | 24.6 ± 6.1 | 23.1 ± 11.4 | 23.1 ± 5.1 | |||
| 6 months | 23.3 ± 4.2 | 25.1 ± 13.5 | 21.7 ± 6.2 | |||
| SGPT (U/L) | Baseline | 25.6 ± 7.6 | 21.6 ± 7.7 | 40.6 ± 30.1 | 0.006 | 0.111 |
| 3 months | 21.6 ± 6.1 | 13.4 ± 5.3 | 20.1 ± 9.9 | |||
| 6 months | 23.3 ± 8.3 | 23.1 ± 21.1 | 23.7 ± 17.9 | |||
| γ-GTP (U/L) | Baseline | 36.7 ± 14.4 | 60.9 ± 47.4 | 43.1 ± 19.9 | 0.042 | 0.332 |
| 3 months | 37.6 ± 17.0 | 52.1 ± 42.3 | 34.3 ± 13.9 | |||
| 6 months | 36.3 ± 13.9 | 56.5 ± 45.9 | 35.9 ± 16.9 | |||
All data are presented as mean ± standard error
γ-GTP γ-glutamyl transpeptidase, HDL high-density lipoprotein, HOMA-IR homeostatic model assessment of insulin resistance, LCAT lecithin–cholesterol acyltransferase, LDL low-density lipoprotein, SGOT serum glutamic oxaloacetic transaminase, SGPT serum glutamate pyruvate transaminase
aGroups: C, control group; M, mastic intake group; M + PA, mastic intake with physical activity group