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The gene expression of GH, IGF-1, and IGFBP-1 in cells stimulated with l-arginine. (A) The mRNA expression levels of GH were quantified in GH3, (B, C) the IGF-1 and IGFBP-1 expression levels in HepG2 cells, respectively, after treatment with l-arginine for 24 h. C, vehicle-treated (doubly distilled water) negative control; Est, 100 nM estradiol (positive control); Arg, l-arginine. **P < 0.01; ***P < 0.001 versus the control group for the ANOVA test
