Effect of ORT on the level of plasma glucose and insulin. In STZ-induced diabetic ICR mouse, ORT (0.6 g/kg BW) and Met (0.6 g/kg BW) were orally administered for 22 days. After 10 days of oral administration, fasting blood glucose (FBG) (A) was measured from mouse tail vein. Concentration of plasma glucose (B) and insulin (C) was measured after euthanization. Values are presented as the mean ± SE. Means with different letters are significantly different at p < 0.05 using Duncan’s multiple range test. NS not significant, NC normal control, DC diabetes control, DORT diabetes + oxyresveratrol; DMet diabetes + metformin