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. 2017 Dec 20;91(1081):20170508. doi: 10.1259/bjr.20170508

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© 2018 The Authors. Published by the British Institute of Radiology

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Figure 4. — (a) Block description of a 2-tissue 4-parameters compartmental kinetic model employed for the widely applicable ¹⁸F-FDG radiotracer in clinical oncology. (b) Mathematical definition of the tracer influx rate constant K_i macro-parameter as a non-linear combination of the individual microparameters K₁, k₂, k₃ and k₄ (rate constants) of the ¹⁸F-FDG compartmental model. (c) Characteristic ¹⁸F-FDG tissue time activity concentration curves (TACs) as modelled with the full 2-tissue compartmental model and published ¹⁸F-FDG measured kinetic parameters. FDG, fludeoxyglucose; TACs, time activity concentration curves.