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. 2018 Jul 3;9(51):29743–29752. doi: 10.18632/oncotarget.25701

Table 1. Cox proportional hazards model results for de novo PS gene expression.

Dataset	Discovery (n = 386)				Validation (n = 164)
Dataset	HR (95% CI)	P-value	Regression coefficient	Risk group expression	HR (95% CI)	P-value	Regression coefficient	Risk group expression
CAD^*	1.44 (1.06-1.95)	0.008^*	0.977	high	2.42 (1.14 – 5.11)	0.017^*	0.715	high
DHODH	1.15 (0.85-1.54)	0.160	0.325	high	1.17 (0.58-2.34)	0.6631	1.25	high
UMPS	1.13 (0.84-1.52)	0.428	-0.346	low	1.58 (0.78-3.21)	0.1987	-0.075	low

Abbreviations: CI, confidence interval; HR, hazard ratio for risk group; ^* indicates significance (P < 0.05).