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. 2018 Jul 3;9(51):29634–29643. doi: 10.18632/oncotarget.25659

Figure 2. Partial protection by TRPC4 knockout.

Figure 2

(A) Western blot data for total brain proteins from wild type (WT) and TRPC4 knockout (C4KO) mice. Using anti-TRPC4 antibody (upper gel) and anti-GAPDH (lower gel, loading control). Each lane is protein for a different mouse. There were 4 mice in the WT group and 4 mice in the C4KO group. (B-D) Data generated for wild type (WT) and TRPC4 knockout mice (TRPC4 KO) in the Open Field Test. (B) Representative track plots, (C) total distance travelled and (D) total freezing time after intraperitoneal injection of vehicle, 1 mg.kg-1 EA or 2 mg.kg-1 EA (n=3 mice per group).