Skip to main content
. 2018 Jul 3;9(51):29810–29819. doi: 10.18632/oncotarget.25629

Table 2. Prognostic factors: univariate analysis.

Variable n Cure (n = 29) Non-cure (n = 14) p-value
Sex
 Male 37 24 13 0.371
 Female 6 5 1
Age
 <75 29 20 9 0.759
 ≥75 14 9 5
Method
 Thoracotomy 39 26 13 0.735
 Video-assisted thoracic surgery 4 3 1
Pathologic stage
 I 21 13 8 0.449
 II, III, IV 22 16 6
Histology
 Squamous cell ca. 16 7 9 0.011
 Non-squamous cell ca. 27 22 5
Procedure
 Pneumonectomy, Bi-lobectomy 11 5 6 0.071
 Others 32 24 8
Pre-operative complications
 Hypertension 14 8 6 0.371
 Chronic obstructive pulmonary disease 6 4 2 0.965
 Administration of steroid 5 1 4 0.016
 Other organs cancer 4 3 1 0.735
 Diabetes mellitus 4 2 2 0.434
 Ischemic heart disease 3 1 2 0.191
 Cerebrovascular disease 3 2 1 0.976
 Interstitial pneumonia 2 0 2 0.037
Date of onset
 <30 days 29 20 9 0.759
 ≥30 days 14 9 5
Cause of empyema
 Bronchial stump fistula 14 6 8 0.017
 Retrograde infection by chest tube 12 12 0 0.005
 Bronchopleural fistula 11 7 4 0.755
 Exacerbation of interstitial pneumonia 4 0 4 0.003
 Intraoperative contamination 3 2 1 0.976
 Surgical site infection 3 3 0 0.212
 Pneumonia 3 3 0 0.212
Microbiology
 MRSA 10 5 5 0.179
 MSSA 9 8 1 0.123
 Pseudomonas aeruginosa 6 4 2 0.965
 Enterobacteriaceae 4 1 3 0.057
 Enterococci 3 2 1 0.976
 Aspergillus 2 1 1 0.590
 Nontuberculous mycobacteria 1 1 0 0.482
 Haemophilus influenzae 1 1 0 0.482
 Anaerobe 4 4 0 0.145
 Gram-positive coccus 3 3 0 0.212
 Non-fermenting Gram-negative bacilli 2 0 2 0.037
 Corynebacterium spp 1 0 1 0.145
 Culture negative 6 3 3 0.326

Abbreviations: MRSA: Methicillin-resistant Staphylococcus aureus; MSSA: Methicillin-susceptible Staphylococcus aureus.