Table 4. Aetiological agents of neonatal sepsis in Nigeria.
Study | Positive cultures (n) | GBS (%) | Unspecified Streptococci (%) | Proteus spp (%) | Pseudomonas spp (%) | K. pneumoniae (%) | E. coli (%) | S. aureus (%) | CoNS* (%) | Others ¶(%) |
---|---|---|---|---|---|---|---|---|---|---|
Medugu 2017 [25] | 7 | 14.3 | - | - | - | 42.9 | - | 42.9 | - | - |
Medugu 2017 [26] | 81 | - | - | - | 8.6 | 11.1 | 3.7 | 59.3 | 6.2 | 11.1 |
Olatunde 2016 [27] | 72 | - | - | 1.4 | 6.9 | 11.1 | 2.8 | 70 | - | 7.8 |
Peterside 2015 [28] | 97 | _ | - | 8.2 | 7.2 | 14.4 | 16.5 | 51.5 | - | 2.2 |
Shobowole 2015[29] | 85 | - | - | 4.7 | - | 36.5 | - | 18.8 | 11.1 | 28.9 |
Onyedibe 2015 [30] | 75 | - | - | 2.7 | 4.0 | 32.0 | 10.7 | 30.7 | 6.7 | 13.2 |
Ekwochi 2014 [31] | 17 | _ | - | - | - | - | 18 | 53 | - | 29 |
Okon 2014 [32] | 70 | _ | - | 1.4 | 2.9 | 21.4 | 8.6 | 56 | 1.4 | 8.3 |
Uzodimma 2013 [33] | 16 | _ | 13 | - | - | 9 | 6 | 56 | - | 16 |
Kingsley 2013 [34] | 91 | - | - | 3.3 | - | 16.5 | 25.3 | 42.9 | 4.4 | 7.6 |
Awoala 2012 and West Peterside [35] | 169 | _ | 0.9 | 5.5 | 3.6 | 58.2 | 8.1 | 20 | 1.8 | 1.9 |
Ogunlesi 2011[37] | 174 | _ | - | 6.3 | 4 | 23 | 11 | 31 | 12.6 | 12.1 |
Nwadioha 2010 [38] | 326 | _ | - | 4.4 | - | 12.3 | 55.1 | 27.6 | - | 0.6 |
Anah 2008 [6] | 363 | _ | 8.3 | 0.5 | 2.8 | 3.3 | - | 53 | - | 32.1 |
Udo 2008 [39] | 178 | - | 8.5 | - | - | 2.2 | - | 65.2 | - | 24.1 |
Fadero 2007 [40] | 32 | _ | - | 18.8 | - | 9.4 | 6.3 | 56.3 | 6.3 | 2.9 |
Ojukwu 2006 [7] | 33 | 3 | 9.0 | 3 | 3 | 9.1 | 18.2 | 45.5 | - | 12.2 |
Iregbu 2006 [41] | 85 | _ | - | - | 4.7 | 43.5 | 1.2 | 40 | 2.4 | 8.2 |
Meremikwu 2005 [42] | 271 | _ | 4.8 | 0.4 | 5.9 | - | - | 51 | 2.2 | 35.7 |
Mokuolu 2002 [43] | 61 | _ | - | - | 1.6 | 16.4 | 4.9 | 29.5 | 24.6 | 23 |
Adejuyigbe 2001 [48] | 66 | _ | - | - | 18.8 | 8.7 | 5.8 | 36.2 | 15.9 | 14.6 |
Antia-Obong 1992 [52] | 100 | _ | 3 | 1 | 1 | 7 | 3 | 45 | - | 40 |
Airede 1992 [45] | 99 | - | - | - | - | 37 | 37 | - | 26 | |
Owa 1988 [47] | 31 | _ | - | - | - | 12.9 | 12.9 | 25.8 | 3.2 | 45.2 |
* CoNS = Coagulase negative Staphylococci. GBS = Group B Streptococcus
¶Other pathogens detected: Salmonella spp, Streptococcus pneumoniae, Serratia marcescens, Haemophilus influenzae, Enterococcus spp, Enterobacter spp.