Figure 1.

Ischemia Simulation Pipeline. Electrogram and imaging data were extracted from experimental preparations of induced acute ischemia in dogs. From imaging data, subject-specific geometric models were generated that contained conforming, subject-specific cardiac fibers definitions and ischemic zone geometries. Intramural electrical potentials were mapped within the geometric models. Intramural and epicardial electrical potentials (recorded from plunge needle and sock electrodes) were also mapped in order to define subject-specific is-chemic regions and to validate simulation results, respectively.