Table 1. Representative listing of aggregate and aggregate associated proteins in oocyt nuclei.
Table 1—source data 1. Retained proteins following depletion of soluble nuclear components.
elife-35224-table1-data1.docx (93.9KB, docx)
DOI: 10.7554/eLife.35224.004
Table 1—source data 2. Key with brief descriptions of the data sets.
elife-35224-table1-data2.docx (65.6KB, docx)
DOI: 10.7554/eLife.35224.005
| Process | Gene name | Function (summarized from www.genecards.org) |
|---|---|---|
| DNA Replication | ||
| TOP2A | Topoisomerase II Alpha, DNA topoisomerase | |
| MCM2 | Minichromosome Maintenance Complex Component 2, involved in replication initiation | |
| POLE | DNA Polymerase Epsilon, Contributes to DNA repair and replication | |
| WRN | Werner Syndrome RecQ Like Helicase, DEAH 5' to 3' DNA with 3' to 5' exonuclease activity | |
| PRIM2 | Primase Subunit 2, DNA directed RNA polymerase that generates lagging | |
| RNA Processing | ||
| GTF2H2 | General Transcription Factor IIH Subunit 2, member of RNA pol II transcription initiation factor IIH complex | |
| SRRM1 | Serine and Arginine Repetitive Matrix 1, Part of pre- and post-splicing multiprotein mRNP complexes | |
| XAB2 | XPA Binding Protein 2, participates in mRNA splicing and nucleotide excision repair | |
| NOLC1 | Nucleolar and Coiled-Body Phosphoprotein, heavily modified regulator of RNA pol I | |
| SRSF5 | Serine Arginine Rich Splicing Factor 5, spliceosome component with an RRM and RS domains | |
| Transcription, DNA-templated | ||
| POLR1C | RNA Pol I subunit C, component of RNA Pol I and III complexes | |
| HSPA8 | Heat Shock Protein Family A Member 8, constitutively expressed member of HSP70 family | |
| NCL | Nucleolin, binds histone H1 to decondense DNA | |
| POLR1A | RNA pol I subunit A, catalytic and largest subunit or RNA Pol I complex | |
| POLR2E | RNA Pol II subunit E, subunit shared between RNA Pol I, II, and III | |
| Ribonucleoprotein Complex Biogenesis | ||
| PES1 | pescadillo, member of PeBoW complex and contributes to ribosome biogenesis, binds BRCA1 | |
| BOP1 | Block of Proliferation 1, participates in rRNA processing and is a member of PeBoW complex | |
| NPM1 | Nucleophosmin, multi-functional nucleolar phosphoprotein | |
| DDX21 | DEAD-Box Helicase 21, facilitates processing or RNA Pol I and II transcripts | |
| FBL | Fibrillarin, rRNA and protein methyltransferase | |