Abbreviations: pCR, pathological complete response; L, lapatinib; P, pertuzumab; T, trastuzumab. *, treatment arms without chemotherapy; a,b, treatment arms included 5-fluorouracil, epirubicin, cyclophosphamide, and docetaxel with different schedules; c, treatment arm included docetaxel and carboplatin. Numbers on top of the bars indicate pCR rate (%).